The Macrophage as Therapeutic Target: 158 (Handbook of Experimental Pharmacology)
The Macrophage as Therapeutic Target: 158 (Handbook of Experimental Pharmacology)
In the past ten years, the rapid growth of molecular & cellular knowledge of macrophages, as a specialized immune system homeostasis & started into offer attractive targets for therapeutic interventions. Macrophages play a central role in a wide spectrum of disease processes resulting from genetically determined lysosomal storage diseases into acute sepsis, chronic inflammation & repair, tissue damage & cell death. Help under-or overactive macrophage clearance, immune effector functions & responses into metabolic disorders, common diseases such as autoimmunity, atherosclerosis, Alzheimer’s disease & major infections, including AIDS & tuberculosis. While the targets of therapeutic intervention on the basis of improved unde
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